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Isavuconazole Therapy Protects Immunosuppressed Mice from Mucormycosis
We studied the in vitro and in vivo efficacies of the investigational drug isavuconazole against mucormycosis due to Rhizopus delemar. Isavuconazole was effective, with MIC and minimal fungicidal concentration (MFC) values ranging between 0.125 and 1.00 μg/ml. A high dose of isavuconazole prolonged...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023778/ https://ncbi.nlm.nih.gov/pubmed/24492363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02301-13 |
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