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Isavuconazole Therapy Protects Immunosuppressed Mice from Mucormycosis
We studied the in vitro and in vivo efficacies of the investigational drug isavuconazole against mucormycosis due to Rhizopus delemar. Isavuconazole was effective, with MIC and minimal fungicidal concentration (MFC) values ranging between 0.125 and 1.00 μg/ml. A high dose of isavuconazole prolonged...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023778/ https://ncbi.nlm.nih.gov/pubmed/24492363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02301-13 |
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