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Isavuconazole Therapy Protects Immunosuppressed Mice from Mucormycosis

We studied the in vitro and in vivo efficacies of the investigational drug isavuconazole against mucormycosis due to Rhizopus delemar. Isavuconazole was effective, with MIC and minimal fungicidal concentration (MFC) values ranging between 0.125 and 1.00 μg/ml. A high dose of isavuconazole prolonged...

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Hlavní autoři: Luo, Guanpingsheng, Gebremariam, Teclegiorgis, Lee, Hongkyu, Edwards, John E., Kovanda, Laura, Ibrahim, Ashraf S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023778/
https://ncbi.nlm.nih.gov/pubmed/24492363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02301-13
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