Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats

Post-translational modifications (PTMs) of proteins regulate various cellular processes. PTMs of polyglutamine-expanded huntingtin (Htt) protein, which causes Huntington’s disease (HD), are likely modulators of HD pathogenesis. Previous studies have identified and characterized several PTMs on exoge...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Proteome Res
Egile Nagusiak: Ratovitski, Tamara, O’Meally, Robert N., Jiang, Mali, Chaerkady, Raghothama, Chighladze, Ekaterine, Stewart, Jacqueline C., Wang, Xiaofang, Arbez, Nicolas, Roby, Elaine, Alexandris, Athanasios, Duan, Wenzhen, Vijayvargia, Ravi, Seong, Ihn Sik, Lavery, Daniel J., Cole, Robert N., Ross, Christopher A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560079/
https://ncbi.nlm.nih.gov/pubmed/28653853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00991
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