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Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats

Post-translational modifications (PTMs) of proteins regulate various cellular processes. PTMs of polyglutamine-expanded huntingtin (Htt) protein, which causes Huntington’s disease (HD), are likely modulators of HD pathogenesis. Previous studies have identified and characterized several PTMs on exoge...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Proteome Res
Main Authors: Ratovitski, Tamara, O’Meally, Robert N., Jiang, Mali, Chaerkady, Raghothama, Chighladze, Ekaterine, Stewart, Jacqueline C., Wang, Xiaofang, Arbez, Nicolas, Roby, Elaine, Alexandris, Athanasios, Duan, Wenzhen, Vijayvargia, Ravi, Seong, Ihn Sik, Lavery, Daniel J., Cole, Robert N., Ross, Christopher A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560079/
https://ncbi.nlm.nih.gov/pubmed/28653853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00991
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