Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats

Post-translational modifications (PTMs) of proteins regulate various cellular processes. PTMs of polyglutamine-expanded huntingtin (Htt) protein, which causes Huntington’s disease (HD), are likely modulators of HD pathogenesis. Previous studies have identified and characterized several PTMs on exoge...

Full description

Saved in:
Bibliographic Details
Published in:J Proteome Res
Main Authors: Ratovitski, Tamara, O’Meally, Robert N., Jiang, Mali, Chaerkady, Raghothama, Chighladze, Ekaterine, Stewart, Jacqueline C., Wang, Xiaofang, Arbez, Nicolas, Roby, Elaine, Alexandris, Athanasios, Duan, Wenzhen, Vijayvargia, Ravi, Seong, Ihn Sik, Lavery, Daniel J., Cole, Robert N., Ross, Christopher A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560079/
https://ncbi.nlm.nih.gov/pubmed/28653853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00991
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items