Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

Native-like trimers of the SOSIP design are being developed as immunogens in human immunodeficiency virus type 1 (HIV-1) vaccine development programs. These trimers display the epitopes for multiple broadly neutralizing antibodies (bNAbs) but can also expose binding sites for some types of nonneutra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Ringe, Rajesh P., Ozorowski, Gabriel, Rantalainen, Kimmo, Struwe, Weston B., Matthews, Katie, Torres, Jonathan L., Yasmeen, Anila, Cottrell, Christopher A., Ketas, Thomas J., LaBranche, Celia C., Montefiori, David C., Cupo, Albert, Crispin, Max, Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Klasse, P. J., Moore, John P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512241/
https://ncbi.nlm.nih.gov/pubmed/28539451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00677-17
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