Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4(+) T cells into distinct effector subsets

Naive CD4(+) T cells differentiate into specific effector subsets—Th1, Th2, Th17, and T follicular helper (Tfh)—that provide immunity against pathogen infection. The signaling pathways involved in generating these effector cells are partially known. However, the effects of mutations underlying human...

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Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Ma, Cindy S., Wong, Natalie, Rao, Geetha, Nguyen, Akira, Avery, Danielle T., Payne, Kathryn, Torpy, James, O’Young, Patrick, Deenick, Elissa, Bustamante, Jacinta, Puel, Anne, Okada, Satoshi, Kobayashi, Masao, Martinez-Barricarte, Ruben, Elliott, Michael, Sebnem Kilic, Sara, El Baghdadi, Jamila, Minegishi, Yoshiyuki, Bousfiha, Aziz, Robertson, Nic, Hambleton, Sophie, Arkwright, Peter D., French, Martyn, Blincoe, Annaliesse K., Hsu, Peter, Campbell, Dianne E., Stormon, Michael O., Wong, Melanie, Adelstein, Stephen, Fulcher, David A., Cook, Matthew C., Stepensky, Polina, Boztug, Kaan, Beier, Rita, Ikincioğullari, Aydan, Ziegler, John B., Gray, Paul, Picard, Capucine, Boisson-Dupuis, Stéphanie, Phan, Tri Giang, Grimbacher, Bodo, Warnatz, Klaus, Holland, Steven M., Uzel, Gulbu, Casanova, Jean-Laurent, Tangye, Stuart G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2016
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986526/
https://ncbi.nlm.nih.gov/pubmed/27401342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151467
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