14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency

BACKGROUND: Inducible co-stimulator (ICOS) deficiency was the first monogenic defect reported to cause common variable immunodeficiency (CVID)-like disease in 2003. Since then, 16 patients have been reported worldwide with an increasing range of clinical phenotypes. OBJECTIVE: We sought to compare t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schepp, Johanna, Chou, Janet, Skrabl-Baumgartner, Andrea, Arkwright, Peter D., Engelhardt, Karin R., Hambleton, Sophie, Morio, Tomohiro, Röther, Ekkehard, Warnatz, Klaus, Geha, Raif, Grimbacher, Bodo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561331/
https://ncbi.nlm.nih.gov/pubmed/28861081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00964
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