Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4(+) T cells into distinct effector subsets

Naive CD4(+) T cells differentiate into specific effector subsets—Th1, Th2, Th17, and T follicular helper (Tfh)—that provide immunity against pathogen infection. The signaling pathways involved in generating these effector cells are partially known. However, the effects of mutations underlying human...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Ma, Cindy S., Wong, Natalie, Rao, Geetha, Nguyen, Akira, Avery, Danielle T., Payne, Kathryn, Torpy, James, O’Young, Patrick, Deenick, Elissa, Bustamante, Jacinta, Puel, Anne, Okada, Satoshi, Kobayashi, Masao, Martinez-Barricarte, Ruben, Elliott, Michael, Sebnem Kilic, Sara, El Baghdadi, Jamila, Minegishi, Yoshiyuki, Bousfiha, Aziz, Robertson, Nic, Hambleton, Sophie, Arkwright, Peter D., French, Martyn, Blincoe, Annaliesse K., Hsu, Peter, Campbell, Dianne E., Stormon, Michael O., Wong, Melanie, Adelstein, Stephen, Fulcher, David A., Cook, Matthew C., Stepensky, Polina, Boztug, Kaan, Beier, Rita, Ikincioğullari, Aydan, Ziegler, John B., Gray, Paul, Picard, Capucine, Boisson-Dupuis, Stéphanie, Phan, Tri Giang, Grimbacher, Bodo, Warnatz, Klaus, Holland, Steven M., Uzel, Gulbu, Casanova, Jean-Laurent, Tangye, Stuart G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2016
Onderwerpen:
Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986526/
https://ncbi.nlm.nih.gov/pubmed/27401342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151467
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items