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Fibrin deposition following bile duct injury limits fibrosis through an α(M)β(2)-dependent mechanism

Coagulation cascade activation and fibrin deposits have been implicated or observed in diverse forms of liver damage. Given that fibrin amplifies pathological inflammation in several diseases through the integrin receptor α(M)β(2), we tested the hypothesis that disruption of the fibrin(ogen)-α(M)β(2...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Joshi, Nikita, Kopec, Anna K., Ray, Jessica L., Cline-Fedewa, Holly, Nawabi, Atta, Schmitt, Timothy, Nault, Rance, Zacharewski, Timothy R., Rockwell, Cheryl E., Flick, Matthew J., Luyendyk, James P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891955/
https://ncbi.nlm.nih.gov/pubmed/26921287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-670703
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