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Fibrin deposition following bile duct injury limits fibrosis through an α(M)β(2)-dependent mechanism
Coagulation cascade activation and fibrin deposits have been implicated or observed in diverse forms of liver damage. Given that fibrin amplifies pathological inflammation in several diseases through the integrin receptor α(M)β(2), we tested the hypothesis that disruption of the fibrin(ogen)-α(M)β(2...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891955/ https://ncbi.nlm.nih.gov/pubmed/26921287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-670703 |
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