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Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis

The etiology of chronic bile duct injury and fibrosis in patients with autoimmune cholestatic liver diseases is complex, and likely involves immune cells such as lymphocytes. However, most models of biliary fibrosis are not autoimmune in nature. Biliary fibrosis can be induced experimentally by prol...

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Detalhes bibliográficos
Publicado no:Toxicology
Main Authors: Joshi, Nikita, Kopec, Anna K., Cline-Fedewa, Holly, Luyendyk, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338728/
https://ncbi.nlm.nih.gov/pubmed/28049044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2016.12.009
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