Hepatocyte tissue factor activates the coagulation cascade in mice

In this study, we characterized tissue factor (TF) expression in mouse hepatocytes (HPCs) and evaluated its role in mouse models of HPC transplantation and acetaminophen (APAP) overdose. TF expression was significantly reduced in isolated HPCs and liver homogenates from TF(flox/flox)/albumin-Cre mic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sullivan, Bradley P., Kopec, Anna K., Joshi, Nikita, Cline, Holly, Brown, Juliette A., Bishop, Stephanie C., Kassel, Karen M., Rockwell, Cheryl, Mackman, Nigel, Luyendyk, James P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2013
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591805/
https://ncbi.nlm.nih.gov/pubmed/23305736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-455436
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