Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

Tissue factor (TF) is the primary activator of the coagulation cascade. During endotoxemia, TF expression leads to disseminated intravascular coagulation. However, the relative contribution of TF expression by different cell types to the activation of coagulation has not been defined. In this study,...

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Autori principali: Pawlinski, Rafal, Wang, Jian-Guo, Owens, A. Phillip, Williams, Julie, Antoniak, Silvio, Tencati, Michael, Luther, Thomas, Rowley, Jesse W., Low, Elizabeth N., Weyrich, Andrew S., Mackman, Nigel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918334/
https://ncbi.nlm.nih.gov/pubmed/20410508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-259267
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