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Multiple roles of the coagulation protease cascade during virus infection

The coagulation cascade is activated during viral infections. This response may be part of the host defense system to limit spread of the pathogen. However, excessive activation of the coagulation cascade can be deleterious. In fact, inhibition of the tissue factor/factor VIIa complex reduced mortal...

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Main Authors: Antoniak, Silvio, Mackman, Nigel
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999750/
https://ncbi.nlm.nih.gov/pubmed/24632711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-526277
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