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Multiple roles of the coagulation protease cascade during virus infection

The coagulation cascade is activated during viral infections. This response may be part of the host defense system to limit spread of the pathogen. However, excessive activation of the coagulation cascade can be deleterious. In fact, inhibition of the tissue factor/factor VIIa complex reduced mortal...

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Bibliografiske detaljer
Main Authors: Antoniak, Silvio, Mackman, Nigel
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999750/
https://ncbi.nlm.nih.gov/pubmed/24632711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-526277
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