Deletion of Mouse Rad9 Causes Abnormal Cellular Responses to DNA Damage, Genomic Instability, and Embryonic Lethality

The fission yeast Schizosaccharomyces pombe rad9 gene promotes cell survival through activation of cell cycle checkpoints induced by DNA damage. Mouse embryonic stem cells with a targeted deletion of Mrad9, the mouse ortholog of this gene, were created to evaluate its function in mammals. Mrad9(−/−)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Hopkins, Kevin M., Auerbach, Wojtek, Wang, Xiang Yuan, Hande, M. Prakash, Hang, Haiying, Wolgemuth, Debra J., Joyner, Alexandra L., Lieberman, Howard B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2004
Gaiak:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479733/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.7235-7248.2004
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak