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Mouse Rad9b is essential for embryonic development and promotes resistance to DNA damage

RAD9 participates in promoting resistance to DNA damage, cell cycle checkpoint control, DNA repair, apoptosis, embryogenesis, and regulation of transcription. A paralogue of RAD9 (named RAD9B) has been identified. To define the function of mouse Rad9b (Mrad9b), embryonic stem (ES) cells with a targe...

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Détails bibliographiques
Auteurs principaux: Leloup, Corinne, Hopkins, Kevin M., Wang, Xiangyuan, Zhu, Aiping, Wolgemuth, Debra J., Lieberman, Howard B.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967720/
https://ncbi.nlm.nih.gov/pubmed/20842695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22415
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