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Mouse Rad9b is essential for embryonic development and promotes resistance to DNA damage

RAD9 participates in promoting resistance to DNA damage, cell cycle checkpoint control, DNA repair, apoptosis, embryogenesis, and regulation of transcription. A paralogue of RAD9 (named RAD9B) has been identified. To define the function of mouse Rad9b (Mrad9b), embryonic stem (ES) cells with a targe...

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Autors principals: Leloup, Corinne, Hopkins, Kevin M., Wang, Xiangyuan, Zhu, Aiping, Wolgemuth, Debra J., Lieberman, Howard B.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967720/
https://ncbi.nlm.nih.gov/pubmed/20842695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22415
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