Deletion of the Mouse P450c17 Gene Causes Early Embryonic Lethality

Dehydroepiandrosterone (DHEA), a 19-carbon precursor of sex steroids, is abundantly produced in the human but not the mouse adrenal. However, mice produce DHEA and DHEA-sulfate (DHEAS) in the fetal brain. DHEA stimulates axonal growth from specific populations of mouse neocortical neurons in vitro,...

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Detalhes bibliográficos
Main Authors: Bair, Susanna R., Mellon, Synthia H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419874/
https://ncbi.nlm.nih.gov/pubmed/15169901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5383-5390.2004
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