Targeted Deletion of the Murine apobec-1 Complementation Factor (acf) Gene Results in Embryonic Lethality

apobec-1 complementation factor (ACF) is an hnRNP family member which functions as the obligate RNA binding subunit of the core enzyme mediating C-to-U editing of the nuclear apolipoprotein B (apoB) transcript. ACF binds to both apoB RNA and apobec-1, the catalytic cytidine deaminase, which then res...

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Autors principals: Blanc, Valerie, Henderson, Jeffrey O., Newberry, Elizabeth P., Kennedy, Susan, Luo, Jianyang, Davidson, Nicholas O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190267/
https://ncbi.nlm.nih.gov/pubmed/16055734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7260-7269.2005
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