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Apobec-1 Complementation Factor Modulates Liver Regeneration by Post-transcriptional Regulation of Interleukin-6 mRNA Stability

Apobec-1 complementation factor (ACF) is the RNA binding subunit of a core complex that mediates C to U RNA editing of apolipoprotein B (apoB) mRNA. Targeted deletion of the murine Acf gene is early embryonic lethal and Acf(−/−) blastocysts fail to implant and proliferate, suggesting that ACF plays...

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Autori principali: Blanc, Valerie, Sessa, Kimberly J., Kennedy, Susan, Luo, Jianyang, Davidson, Nicholas O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885197/
https://ncbi.nlm.nih.gov/pubmed/20406809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115147
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