Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism in Apobec-1(−/−) Mice Lead to Increased Gallstone Susceptibility

Quantitative trait mapping in mice identified a susceptibility locus for gallstones (Lith6) spanning the Apobec-1 locus, the structural gene encoding the RNA-specific cytidine deaminase responsible for production of apolipoprotein B48 in mammalian small intestine and rodent liver. This observation p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xie, Yan, Blanc, Valerie, Kerr, Thomas A., Kennedy, Susan, Luo, Jianyang, Newberry, Elizabeth P., Davidson, Nicholas O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719322/
https://ncbi.nlm.nih.gov/pubmed/19386592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010173
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados