Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

Bacillus anthracis, the causative agent of anthrax, secretes three polypeptides, which form the bipartite lethal and edema toxins (LT and ET, respectively). The common component in these toxins, protective antigen (PA), is responsible for binding to cellular receptors and translocating the lethal fa...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Vaccine Immunol
Egile Nagusiak: Moayeri, Mahtab, Tremblay, Jacqueline M., Debatis, Michelle, Dmitriev, Igor P., Kashentseva, Elena A., Yeh, Anthony J., Cheung, Gordon Y. C., Curiel, David T., Leppla, Stephen, Shoemaker, Charles B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Clinical Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783422/
https://ncbi.nlm.nih.gov/pubmed/26740390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00611-15
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