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CA-074Me Protection against Anthrax Lethal Toxin

Anthrax lethal toxin (LT) activates the NLRP1b (NALP1b) inflammasome and caspase-1 in macrophages from certain inbred mouse strains, but the mechanism by which this occurs is poorly understood. We report here that similar to several NLRP3 (NALP3, cryopyrin)-activating stimuli, LT activation of the N...

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Autori principali: Newman, Zachary L., Leppla, Stephen H., Moayeri, Mahtab
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747948/
https://ncbi.nlm.nih.gov/pubmed/19635822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00730-09
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