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Anthrax Lethal Toxin Induces Ketotifen-Sensitive Intradermal Vascular Leakage in Certain Inbred Mice

Bacillus anthracis lethal toxin (LT) is a bipartite toxin composed of protective antigen (PA) and lethal factor (LF). Injection of LT produces clinical signs characteristic of anthrax infection, including pleural edema and vascular collapse in various animal models. We utilized the classic Miles lea...

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Detalhes bibliográficos
Main Authors: Gozes, Yehoshua, Moayeri, Mahtab, Wiggins, Jason F., Leppla, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360369/
https://ncbi.nlm.nih.gov/pubmed/16428776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1266-1272.2006
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