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Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages

Anthrax lethal toxin (LT) is an important virulence factor for Bacillus anthracis. In mice, LT lyses macrophages from certain inbred strains in less than two hours by activating the Nlrp1b inflammasome and caspase-1, while macrophages from other strains remain resistant to the toxin’s effects. We an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Newman, Zachary L., Crown, Devorah, Leppla, Stephen H., Moayeri, Mahtab
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925535/
https://ncbi.nlm.nih.gov/pubmed/20638366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.039
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