Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

Bacillus anthracis, the causative agent of anthrax, secretes three polypeptides, which form the bipartite lethal and edema toxins (LT and ET, respectively). The common component in these toxins, protective antigen (PA), is responsible for binding to cellular receptors and translocating the lethal fa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Moayeri, Mahtab, Tremblay, Jacqueline M., Debatis, Michelle, Dmitriev, Igor P., Kashentseva, Elena A., Yeh, Anthony J., Cheung, Gordon Y. C., Curiel, David T., Leppla, Stephen, Shoemaker, Charles B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Clinical Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783422/
https://ncbi.nlm.nih.gov/pubmed/26740390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00611-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados