טוען...
The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics
The pathological accumulation of abnormally hyperphosphorylated and aggregated tau, a neuronal microtubule (MT)-associated protein that functions to maintain MT stability, is implicated in a number of hereditary and sporadic neurodegenerative diseases including frontotemporal dementia and Alzheimer&...
שמור ב:
| הוצא לאור ב: | Hum Mol Genet |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560066/ https://ncbi.nlm.nih.gov/pubmed/25882706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv135 |
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