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Increased Susceptibility to Methotrexate-Induced Toxicity in Nonalcoholic Steatohepatitis
Hepatic drug metabolizing enzymes and transporters play a crucial role in determining the fate of drugs, and alterations in liver function can place individuals at greater risk for adverse drug reactions (ADRs). We have shown that nonalcoholic steatohepatitis (NASH) leads to changes in the expressio...
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| Publicado en: | Toxicol Sci |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334808/ https://ncbi.nlm.nih.gov/pubmed/25080921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu156 |
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