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DNA binding specificities of the long zinc-finger recombination protein PRDM9

BACKGROUND: Meiotic recombination ensures proper segregation of homologous chromosomes and creates genetic variation. In many organisms, recombination occurs at limited sites, termed 'hotspots', whose positions in mammals are determined by PR domain member 9 (PRDM9), a long-array zinc-fing...

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Bibliographische Detailangaben
Hauptverfasser: Billings, Timothy, Parvanov, Emil D, Baker, Christopher L, Walker, Michael, Paigen, Kenneth, Petkov, Petko M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053984/
https://ncbi.nlm.nih.gov/pubmed/23618393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-4-r35
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