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Prdm9 Controls Activation of Mammalian Recombination Hotspots

Mammalian meiotic recombination, which preferentially occurs at specialized sites called hotspots, assures the orderly segregation of meiotic chromosomes and creates genetic variation among offspring. A locus on mouse Chr 17, that controls activation of recombination at multiple distant hotspots, ha...

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Bibliografiske detaljer
Main Authors: Parvanov, Emil D., Petkov, Petko M., Paigen, Kenneth
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821451/
https://ncbi.nlm.nih.gov/pubmed/20044538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1181495
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