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Prdm9 Controls Activation of Mammalian Recombination Hotspots

Mammalian meiotic recombination, which preferentially occurs at specialized sites called hotspots, assures the orderly segregation of meiotic chromosomes and creates genetic variation among offspring. A locus on mouse Chr 17, that controls activation of recombination at multiple distant hotspots, ha...

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Bibliografische gegevens
Hoofdauteurs: Parvanov, Emil D., Petkov, Petko M., Paigen, Kenneth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821451/
https://ncbi.nlm.nih.gov/pubmed/20044538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1181495
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