DNA binding specificities of the long zinc-finger recombination protein PRDM9

BACKGROUND: Meiotic recombination ensures proper segregation of homologous chromosomes and creates genetic variation. In many organisms, recombination occurs at limited sites, termed 'hotspots', whose positions in mammals are determined by PR domain member 9 (PRDM9), a long-array zinc-fing...

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Main Authors: Billings, Timothy, Parvanov, Emil D, Baker, Christopher L, Walker, Michael, Paigen, Kenneth, Petkov, Petko M
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053984/
https://ncbi.nlm.nih.gov/pubmed/23618393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-4-r35
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