DNA binding specificities of the long zinc-finger recombination protein PRDM9

BACKGROUND: Meiotic recombination ensures proper segregation of homologous chromosomes and creates genetic variation. In many organisms, recombination occurs at limited sites, termed 'hotspots', whose positions in mammals are determined by PR domain member 9 (PRDM9), a long-array zinc-fing...

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Bibliografiske detaljer
Main Authors: Billings, Timothy, Parvanov, Emil D, Baker, Christopher L, Walker, Michael, Paigen, Kenneth, Petkov, Petko M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053984/
https://ncbi.nlm.nih.gov/pubmed/23618393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-4-r35
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