Circadian Rhythms: Phosphorylating the CLOCK

Por Baker, Christopher L., Dunlap, Jay C.
Publicado em 2010

The circadian clock of Neurospora crassa: The Neurospora circadian rhythm is controlled through a negative feedback loop centered on the rhythmic production and phosphorylation of...

Por Baker, Christopher L., Loros, Jennifer J., Dunlap, Jay C.
Publicado em 2011

Post-Translational Modifications in Circadian Rhythms

Por Mehra, Arun, Baker, Christopher L., Loros, Jennifer J., Dunlap, Jay C.
Publicado em 2009

PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration

Por Baker, Christopher L., Walker, Michael, Kajita, Shimpei, Petkov, Petko M., Paigen, Kenneth
Publicado em 2014

Fungal Functional Genomics: Tunable Knockout-Knock-in Expression and Tagging Strategies

Por Larrondo, Luis F., Colot, Hildur V., Baker, Christopher L., Loros, Jennifer J., Dunlap, Jay C.
Publicado em 2009

Quantitative Proteomics Reveals a Dynamic Interactome and Phase-specific Phosphorylation in the Neurospora Circadian Clock

Por Baker, Christopher L., Kettenbach, Arminja N., Loros, Jennifer J., Gerber, Scott A., Dunlap, Jay C.
Publicado em 2009

DNA binding specificities of the long zinc-finger recombination protein PRDM9

Por Billings, Timothy, Parvanov, Emil D, Baker, Christopher L, Walker, Michael, Paigen, Kenneth, Petkov, Petko M
Publicado em 2013

Decoupling circadian clock protein turnover from circadian period determination

Por Larrondo, Luis F., Olivares-Yañez, Consuelo, Baker, Christopher L., Loros, Jennifer J., Dunlap, Jay C.
Publicado no Science (2015)

A role for Casein Kinase 2 in the mechanism underlying circadian temperature compensation

Por Mehra, Arun, Shi, Mi, Baker, Christopher L., Colot, Hildur V., Loros, Jennifer J., Dunlap, Jay C.
Publicado em 2009

The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo

Por Powers, Natalie R., Parvanov, Emil D., Baker, Christopher L., Walker, Michael, Petkov, Petko M., Paigen, Kenneth
Publicado no PLoS Genet (2016)

Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

Por Baker, Christopher L., Petkova, Pavlina, Walker, Michael, Flachs, Petr, Mihola, Ondrej, Trachtulec, Zdenek, Petkov, Petko M., Paigen, Kenneth
Publicado no PLoS Genet (2015)

PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination

Por Baker, Christopher L., Kajita, Shimpei, Walker, Michael, Saxl, Ruth L., Raghupathy, Narayanan, Choi, Kwangbom, Petkov, Petko M., Paigen, Kenneth
Publicado no PLoS Genet (2015)

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

Por Taher, Jennifer, Baker, Christopher L., Cuizon, Carmelle, Masoudpour, Hassan, Zhang, Rianna, Farr, Sarah, Naples, Mark, Bourdon, Celine, Pausova, Zdenka, Adeli, Khosrow
Publicado no Mol Metab (2014)

Identification of a QTL in Mus musculus for Alcohol Preference, Withdrawal, and Ap3m2 Expression Using Integrative Functional Genomics and Precision Genetics

Por Bubier, Jason A., Jay, Jeremy J., Baker, Christopher L., Bergeson, Susan E., Ohno, Hiroshi, Metten, Pamela, Crabbe, John C., Chesler, Elissa J.
Publicado em 2014

Nuclear Localization of PRDM9 and Its Role in Meiotic Chromatin Modifications and Homologous Synapsis

Por Sun, Fengyun, Fujiwara, Yasuhiro, Reinholdt, Laura G., Hu, Jianjun, Saxl, Ruth L., Baker, Christopher L., Petkov, Petko M., Paigen, Kenneth, Handel, Mary Ann
Publicado no Chromosoma (2015)

Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage

Por Walker, Michael, Billings, Timothy, Baker, Christopher L., Powers, Natalie, Tian, Hui, Saxl, Ruth L., Choi, Kwangbom, Hibbs, Matthew A., Carter, Gregory W., Handel, Mary Ann, Paigen, Kenneth, Petkov, Petko M.
Publicado no Epigenetics Chromatin (2015)

Health and population effects of rare gene knockouts in adult humans with related parents

Por Narasimhan, Vagheesh M., Hunt, Karen A., Mason, Dan, Baker, Christopher L., Karczewski, Konrad J., Barnes, Michael R., Barnett, Anthony H., Bates, Chris, Bellary, Srikanth, Bockett, Nicholas A., Giorda, Kristina, Griffiths, Christopher J., Hemingway, Harry, Jia, Zhilong, Kelly, M. Ann, Khawaja, Hajrah A., Lek, Monkol, McCarthy, Shane, McEachan, Rosie, O’Donnell-Luria, Anne, Paigen, Kenneth, Parisinos, Constantinos A., Sheridan, Eamonn, Southgate, Laura, Tee, Louise, Thomas, Mark, Xue, Yali, Schnall-Levin, Michael, Petkov, Petko M., Tyler-Smith, Chris, Maher, Eamonn R., Trembath, Richard C., MacArthur, Daniel G., Wright, John, Durbin, Richard, van Heel, David A.
Publicado no Science (2016)