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Nuclear Localization of PRDM9 and Its Role in Meiotic Chromatin Modifications and Homologous Synapsis

Developmental progress of germ cells through meiotic phases is closely tied to ongoing meiotic recombination. In mammals, recombination preferentially occurs in genomic regions known as hotspots; the protein that activates these hotspots is PRDM9, containing a genetically variable zinc-finger domain...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Chromosoma
Päätekijät: Sun, Fengyun, Fujiwara, Yasuhiro, Reinholdt, Laura G., Hu, Jianjun, Saxl, Ruth L., Baker, Christopher L., Petkov, Petko M., Paigen, Kenneth, Handel, Mary Ann
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550572/
https://ncbi.nlm.nih.gov/pubmed/25894966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-015-0511-3
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