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Nuclear Localization of PRDM9 and Its Role in Meiotic Chromatin Modifications and Homologous Synapsis
Developmental progress of germ cells through meiotic phases is closely tied to ongoing meiotic recombination. In mammals, recombination preferentially occurs in genomic regions known as hotspots; the protein that activates these hotspots is PRDM9, containing a genetically variable zinc-finger domain...
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| Publicado no: | Chromosoma |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550572/ https://ncbi.nlm.nih.gov/pubmed/25894966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-015-0511-3 |
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