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Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard
In many mammals, genomic sites for recombination are determined by the histone methyltransferase PRMD9. Some mouse strains lacking PRDM9 are infertile, but instances of fertility or semifertility in the absence of PRDM9 have been reported in mice, canines, and a human female. Such findings raise the...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608834/ https://ncbi.nlm.nih.gov/pubmed/33097538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb6606 |
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