GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

BACKGROUND/OBJECTIVES: Fasting dyslipidemia is commonly observed in insulin resistant states and mechanistically linked to hepatic overproduction of very low density lipoprotein (VLDL). Recently, the incretin hormone glucagon-like peptide-1 (GLP-1) has been implicated in ameliorating dyslipidemia as...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Taher, Jennifer, Baker, Christopher L., Cuizon, Carmelle, Masoudpour, Hassan, Zhang, Rianna, Farr, Sarah, Naples, Mark, Bourdon, Celine, Pausova, Zdenka, Adeli, Khosrow
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264039/
https://ncbi.nlm.nih.gov/pubmed/25506548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.09.005
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