Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

Genetic recombination during meiosis functions to increase genetic diversity, promotes elimination of deleterious alleles, and helps assure proper segregation of chromatids. Mammalian recombination events are concentrated at specialized sites, termed hotspots, whose locations are determined by PRDM9...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Genet
Main Authors: Baker, Christopher L., Petkova, Pavlina, Walker, Michael, Flachs, Petr, Mihola, Ondrej, Trachtulec, Zdenek, Petkov, Petko M., Paigen, Kenneth
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569383/
https://ncbi.nlm.nih.gov/pubmed/26368021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005512
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items