Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

Genetic recombination during meiosis functions to increase genetic diversity, promotes elimination of deleterious alleles, and helps assure proper segregation of chromatids. Mammalian recombination events are concentrated at specialized sites, termed hotspots, whose locations are determined by PRDM9...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Baker, Christopher L., Petkova, Pavlina, Walker, Michael, Flachs, Petr, Mihola, Ondrej, Trachtulec, Zdenek, Petkov, Petko M., Paigen, Kenneth
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569383/
https://ncbi.nlm.nih.gov/pubmed/26368021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005512
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