Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

The aggregation and deposition of amyloid-β (Aβ) peptides are believed to be central events in the pathogenesis of Alzheimer’s disease (AD). Inoculation of brain homogenates containing Aβ aggregates into susceptible transgenic mice accelerated Aβ deposition, suggesting that Aβ aggregates are capable...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stöhr, Jan, Watts, Joel C., Mensinger, Zachary L., Oehler, Abby, Grillo, Sunny K., DeArmond, Stephen J., Prusiner, Stanley B., Giles, Kurt
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390876/
https://ncbi.nlm.nih.gov/pubmed/22711819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206555109
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