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Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein
Currently, there are no animal models of the most common human prion disorder, sporadic Creutzfeldt-Jakob disease (CJD), in which prions are formed spontaneously from wild-type (WT) prion protein (PrP). Interestingly, bank voles (BV) exhibit an unprecedented promiscuity for diverse prion isolates, a...
Gorde:
| Egile Nagusiak: | , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295307/ https://ncbi.nlm.nih.gov/pubmed/22331873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121556109 |
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