Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

The aggregation and deposition of amyloid-β (Aβ) peptides are believed to be central events in the pathogenesis of Alzheimer’s disease (AD). Inoculation of brain homogenates containing Aβ aggregates into susceptible transgenic mice accelerated Aβ deposition, suggesting that Aβ aggregates are capable...

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Bibliografske podrobnosti
Main Authors: Stöhr, Jan, Watts, Joel C., Mensinger, Zachary L., Oehler, Abby, Grillo, Sunny K., DeArmond, Stephen J., Prusiner, Stanley B., Giles, Kurt
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390876/
https://ncbi.nlm.nih.gov/pubmed/22711819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206555109
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