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Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions
The aggregation and deposition of amyloid-β (Aβ) peptides are believed to be central events in the pathogenesis of Alzheimer’s disease (AD). Inoculation of brain homogenates containing Aβ aggregates into susceptible transgenic mice accelerated Aβ deposition, suggesting that Aβ aggregates are capable...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390876/ https://ncbi.nlm.nih.gov/pubmed/22711819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206555109 |
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