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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

An increasing number of studies continue to show that the amyloid β (Aβ) peptide adopts an alternative conformation and acquires transmissibility; hence, it becomes a prion. Here, we report on the attributes of two strains of Aβ prions formed from synthetic Aβ peptides composed of either 40 or 42 re...

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Hlavní autoři: Stöhr, Jan, Condello, Carlo, Watts, Joel C., Bloch, Lillian, Oehler, Abby, Nick, Mimi, DeArmond, Stephen J., Giles, Kurt, DeGrado, William F., Prusiner, Stanley B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104853/
https://ncbi.nlm.nih.gov/pubmed/24982137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408968111
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