Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

An increasing number of studies argues that self-propagating protein conformations (i.e., prions) feature in the pathogenesis of several common neurodegenerative diseases. Mounting evidence contends that aggregates of the amyloid-β (Aβ) peptide become self-propagating in Alzheimer’s disease (AD) pat...

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Main Authors: Watts, Joel C., Condello, Carlo, Stöhr, Jan, Oehler, Abby, Lee, Joanne, DeArmond, Stephen J., Lannfelt, Lars, Ingelsson, Martin, Giles, Kurt, Prusiner, Stanley B.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104857/
https://ncbi.nlm.nih.gov/pubmed/24982139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408900111
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