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Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease

Transgenic (Tg) mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic mechanisms related to Aβ accumulation. However, assessing disease status in these animals has required time-consuming behavioral assessments or postmortem neuropathological analysis. H...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Watts, Joel C., Giles, Kurt, Grillo, Sunny K., Lemus, Azucena, DeArmond, Stephen J., Prusiner, Stanley B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038719/
https://ncbi.nlm.nih.gov/pubmed/21262831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019034108
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