Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

Metabolites in the kynurenine pathway of tryptophan degradation are thought to play an important role in neurodegenerative disorders such as Alzheimer’s disease and Huntington’s disease. Metabolites that cause glutamate receptor-mediated excitotoxicity and free radical formation are elevated in the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zwilling, Daniel, Huang, Shao-Yi, Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Guidetti, Paolo, Wu, Hui-Qiu, Lee, Jason, Truong, Jennifer, Andrews-Zwilling, Yaisa, Hsieh, Eric W., Louie, Jamie Y., Wu, Tiffany, Scearce-Levie, Kimberly, Patrick, Christina, Adame, Anthony, Giorgini, Flaviano, Moussaoui, Saliha, Laue, Grit, Rassoulpour, Arash, Flik, Gunnar, Huang, Yadong, Muchowski, Joseph M., Masliah, Eliezer, Schwarcz, Robert, Muchowski, Paul J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118409/
https://ncbi.nlm.nih.gov/pubmed/21640374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.05.020
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg