載入...

DYSFUNCTIONAL KYNURENINE PATHWAY METABOLISM IN THE R6/2 MOUSE MODEL OF HUNTINGTON’S DISEASE

Elevated concentrations of neurotoxic metabolites of the kynurenine pathway (KP) of tryptophan degradation may play a causative role in Huntington’s disease (HD). The brain levels of one of these compounds, 3-hydroxykynurenine (3-HK), are increased in both HD and several mouse models of the disease....

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Sathyasaikumar, Korrapati V., Stachowski, Erin K., Amori, Laura, Guidetti, Paolo, Muchowski, Paul J., Schwarcz, Robert
格式: Artigo
語言:Inglês
出版: 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721540/
https://ncbi.nlm.nih.gov/pubmed/20236387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06675.x
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!