Design of a Flexible Cell-Based Assay for the Evaluation of Heat Shock Protein 70 Expression Modulators

Heat shock protein 70 (Hsp70) is a chaperone protein that helps protect against cellular stress, a function that may be co-opted to fight human diseases. In particular, the upregulation of Hsp70 can suppress the neurotoxicity of misfolded proteins, suggesting possible therapeutic strategies in neuro...

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Autori principali: Ahn, James H., Luo, Wenjie, Kim, Joungnam, Rodina, Anna, Clement, Cristina C., Aguirre, Julia, Sun, Weilin, Kang, Yanlong, Maharaj, Ronnie, Moulick, Kamalika, Zatorska, Danuta, Kokoszka, Malgorzata, Brodsky, Jeffrey L., Chiosis, Gabriela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2011
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102259/
https://ncbi.nlm.nih.gov/pubmed/21133677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0327
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