Design of a Flexible Cell-Based Assay for the Evaluation of Heat Shock Protein 70 Expression Modulators

Heat shock protein 70 (Hsp70) is a chaperone protein that helps protect against cellular stress, a function that may be co-opted to fight human diseases. In particular, the upregulation of Hsp70 can suppress the neurotoxicity of misfolded proteins, suggesting possible therapeutic strategies in neuro...

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Détails bibliographiques
Auteurs principaux: Ahn, James H., Luo, Wenjie, Kim, Joungnam, Rodina, Anna, Clement, Cristina C., Aguirre, Julia, Sun, Weilin, Kang, Yanlong, Maharaj, Ronnie, Moulick, Kamalika, Zatorska, Danuta, Kokoszka, Malgorzata, Brodsky, Jeffrey L., Chiosis, Gabriela
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2011
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102259/
https://ncbi.nlm.nih.gov/pubmed/21133677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0327
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