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Design of a Flexible Cell-Based Assay for the Evaluation of Heat Shock Protein 70 Expression Modulators
Heat shock protein 70 (Hsp70) is a chaperone protein that helps protect against cellular stress, a function that may be co-opted to fight human diseases. In particular, the upregulation of Hsp70 can suppress the neurotoxicity of misfolded proteins, suggesting possible therapeutic strategies in neuro...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mary Ann Liebert, Inc.
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102259/ https://ncbi.nlm.nih.gov/pubmed/21133677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0327 |
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