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Design of a Flexible Cell-Based Assay for the Evaluation of Heat Shock Protein 70 Expression Modulators

Heat shock protein 70 (Hsp70) is a chaperone protein that helps protect against cellular stress, a function that may be co-opted to fight human diseases. In particular, the upregulation of Hsp70 can suppress the neurotoxicity of misfolded proteins, suggesting possible therapeutic strategies in neuro...

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Detaylı Bibliyografya
Asıl Yazarlar: Ahn, James H., Luo, Wenjie, Kim, Joungnam, Rodina, Anna, Clement, Cristina C., Aguirre, Julia, Sun, Weilin, Kang, Yanlong, Maharaj, Ronnie, Moulick, Kamalika, Zatorska, Danuta, Kokoszka, Malgorzata, Brodsky, Jeffrey L., Chiosis, Gabriela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102259/
https://ncbi.nlm.nih.gov/pubmed/21133677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0327
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